{"title":"Home page","description":"","products":[{"product_id":"ll-37","title":"LL-37","description":"\u003ch2\u003eLL-37 (5mg) — Cathelicidin Antimicrobial Peptide Research Compound\u003c\/h2\u003e\n\u003cp\u003eOmega Peptides Australia supplies LL-37 (5mg) in Australia from domestic stock, dispatching same day on orders placed before 12pm with a certificate of analysis published for every batch. Often written cathelicidin, LL37 or CAP-18 fragment, it is the human cathelicidin antimicrobial peptide studied for innate immunity.\u003c\/p\u003e\n\u003cp\u003eLL-37 is the only cathelicidin-family antimicrobial peptide found in humans. It is a 37-amino-acid fragment released from the C-terminus of the precursor protein hCAP-18 (human cationic antimicrobial protein of 18 kDa, encoded by the CAMP gene) when the protein is cleaved by proteinase 3 in neutrophils. Its name comes from the two leucine residues that begin the sequence and its length of 37 residues. The peptide is strongly cationic, carrying a net charge of about +6, and folds into an amphipathic alpha helix in the presence of membranes. It is often written as LL37, ll 37 or cathelicidin LL-37, and older papers describe it as the CAP-18 fragment or FALL-39.\u003c\/p\u003e\n\u003cp\u003eLL-37 is studied in three overlapping areas: direct antimicrobial and antibiofilm activity against bacteria, fungi and enveloped viruses; innate immune signalling, where it acts as a chemoattractant and modulator of inflammation; and tissue repair, including re-epithelialisation and angiogenesis in wound models. Its antimicrobial action comes from electrostatic binding to negatively charged microbial membranes followed by membrane disruption, while its signalling effects are mediated through host receptors such as formyl peptide receptor 2, the P2X7 receptor and transactivation of the epidermal growth factor receptor.\u003c\/p\u003e\n\u003cp\u003eOmega Peptides Australia supplies LL-37 as a high-purity (≥99% HPLC) COA-verified lyophilised powder in a sealed sterile 5mg vial. Orders placed before 12pm are dispatched the same day from within Australia, and the batch Certificate of Analysis for every lot is published in our \u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCOA library\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroad-spectrum antimicrobial activity\u003c\/strong\u003e LL-37 has been tested against Gram-positive and Gram-negative bacteria, fungi such as Candida, and enveloped viruses in in-vitro models. Its positively charged helix binds the anionic lipids of microbial membranes and inserts into the bilayer, causing leakage and cell death, a physical mechanism that is much harder for microbes to evade than an enzyme-targeting antibiotic.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiofilm disruption\u003c\/strong\u003e At concentrations below those needed to kill bacteria, LL-37 has been shown in laboratory models to inhibit biofilm formation by Pseudomonas aeruginosa and Staphylococcus aureus and to disperse established biofilms. The proposed mechanism involves interference with quorum-sensing systems and the genes that control attachment and twitching motility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInnate immune signalling\u003c\/strong\u003e LL-37 recruits neutrophils, monocytes and T cells through formyl peptide receptor 2 and modulates the response of immune cells to bacterial products. It binds and neutralises lipopolysaccharide, reducing the inflammatory response to endotoxin in cell models, while separately promoting cytokine release through the P2X7 receptor, which is why it is described as an immune modulator rather than simply anti-inflammatory.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWound repair and angiogenesis\u003c\/strong\u003e In skin and epithelial models LL-37 promotes keratinocyte migration and proliferation through EGFR transactivation, and it stimulates endothelial cells to form new vessels. Its expression rises sharply in the margin of healing wounds, and reduced LL-37 has been documented in chronic non-healing ulcers, which drives research interest in topical and matrix-based delivery.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVitamin D and cathelicidin expression\u003c\/strong\u003e The CAMP gene carries a vitamin D response element, and active vitamin D strongly induces LL-37 production in macrophages and epithelial cells. This link is studied in models of tuberculosis, respiratory infection and skin disease, and it is one of the reasons LL-37 is examined alongside other immune research peptides.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAutoimmune and inflammatory skin models\u003c\/strong\u003e LL-37 forms complexes with self-DNA and self-RNA that activate plasmacytoid dendritic cells through TLR9 and TLR7, a pathway implicated in psoriasis and rosacea models. Understanding when the peptide protects and when it drives inflammation is an active area of research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eHow LL-37 works\u003c\/h2\u003e\n\u003cp\u003eLL-37 has two distinct modes of action. The first is direct: in solution it is largely unstructured, but on contact with a negatively charged membrane it adopts an amphipathic alpha helix in which hydrophobic residues line one face and cationic lysine and arginine residues line the other. The peptide accumulates on the microbial surface, inserts into the bilayer and disrupts it through carpet-like and toroidal-pore mechanisms, leading to loss of membrane integrity. Because mammalian membranes are rich in zwitterionic lipids and cholesterol, they are far less susceptible than bacterial membranes at the same concentrations. The second mode is receptor-mediated: LL-37 signals to host cells through formyl peptide receptor 2 (chemotaxis), the P2X7 purinergic receptor (cytokine processing) and transactivation of EGFR (epithelial migration), and it binds lipopolysaccharide and lipoteichoic acid to dampen endotoxin-driven inflammation.\u003c\/p\u003e\n\u003cp\u003eIn biological fluids LL-37 is rapidly degraded by host and bacterial proteases and is partly inactivated by high salt and by binding to serum proteins, so its activity in vitro depends heavily on the assay medium. This short functional lifetime is one reason researchers examine fragments, D-amino-acid analogues and matrix-bound formulations. LL-37 differs from KPV, a three-residue alpha-MSH fragment with anti-inflammatory but no direct antimicrobial activity, and from Thymosin Alpha-1, which acts on adaptive immunity through dendritic cell maturation rather than on microbes directly.\u003c\/p\u003e\n\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCompound\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLL-37 (human cathelicidin antimicrobial peptide)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAlso known as\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLL37, ll 37, cathelicidin LL-37, CAP-18 fragment, LL37 peptide, human cathelicidin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e154947-66-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC205H340N60O53\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4493.3 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES (37 residues)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCategory\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eImmune research\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≥99% HPLC, batch COA supplied\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder in a sealed sterile vial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVial sizes available\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5mg — $119.99\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (lyophilised)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2–8°C short term or −20°C long term, protect from light and moisture, avoid repeated freeze-thaw\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (reconstituted)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2–8°C, use within 28 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water (recommended)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\n\u003ch2\u003eAvailable sizes and pricing\u003c\/h2\u003e\n\u003cp\u003eLL-37 is offered in a single 5mg vial. The per-milligram figure is higher than for shorter peptides because a 37-residue sequence is considerably more demanding to synthesise and purify to ≥99%.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5mg vial — $119.99 (about $24.00 per mg)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMulti-vial pricing (5mg):\u003c\/strong\u003e 2 vials $215.98 (10% off, $107.99 each), 3 vials $314.97 (12.5% off, $104.99 each), 4 vials $407.97 (15% off, $101.99 each). The discount is applied automatically in the cart.\u003c\/p\u003e\n\u003cp\u003eThere is no dedicated kit for LL-37. A vial of \u003ca href=\"\/products\/bacteriostatic-water\"\u003ebacteriostatic water\u003c\/a\u003e is the usual companion purchase for reconstitution.\u003c\/p\u003e\n\n\u003ch2\u003eQuality and COA verification\u003c\/h2\u003e\n\u003cp\u003eEvery batch of LL-37 sold by Omega Peptides Australia is independently tested by Janoshik Analytical. HPLC confirms purity of ≥99%, and mass spectrometry confirms that the measured mass matches the expected 4493 daltons of the full 37-residue sequence, which rules out truncated or mis-synthesised chains. A Certificate of Analysis is issued for every batch and published in our \u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCOA library\u003c\/a\u003e, where the batch number on the vial can be matched to its report. The peptide is supplied lyophilised in a sealed sterile vial because the freeze-dried form is stable for months, whereas LL-37 in solution is vulnerable to oxidation and proteolytic degradation. Vials are packed in protective outer packaging for domestic transit.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently bought together\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/bacteriostatic-water\"\u003eBacteriostatic Water (10mL)\u003c\/a\u003e — $29.99, the diluent used to reconstitute lyophilised LL-37.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1 (10mg)\u003c\/a\u003e — $89.99, the thymic peptide studied for adaptive immune regulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/kpv\"\u003eKPV (10mg)\u003c\/a\u003e — $79.99, the alpha-MSH tripeptide studied in inflammation models.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/bpc-157\"\u003eBPC-157 (10mg)\u003c\/a\u003e — $99.99, the pentadecapeptide used in tissue-repair research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch guides\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/peptide-storage-guide-how-to-store-lyophilised-peptides-properly\"\u003ePeptide storage guide: how to store lyophilised peptides properly\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/coa-testing-explained-research-peptides-australia\"\u003eCOA testing explained for research peptides in Australia\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/research-calculator\"\u003ePeptide reconstitution calculator\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCertificates of Analysis library\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is LL-37?\u003c\/strong\u003e\u003cbr\u003eLL-37 is the human cathelicidin antimicrobial peptide, a 37-amino-acid cationic peptide cleaved from the precursor protein hCAP-18 and produced by neutrophils, macrophages and epithelial cells as part of innate immunity. It has a molecular weight of about 4,493 daltons and forms an amphipathic alpha helix on membranes. Omega Peptides Australia supplies it as a lyophilised research-grade powder in 5mg vials for in-vitro laboratory use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is LL-37 also known as?\u003c\/strong\u003e\u003cbr\u003eIt is also written as LL37, ll 37 or LL-37 peptide, and is often called cathelicidin LL-37 or human cathelicidin. Because it is cut from the precursor hCAP-18, it is sometimes labelled the CAP-18 fragment, and an early 39-residue form was named FALL-39. All of these names refer to the same human antimicrobial peptide.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does LL-37 work?\u003c\/strong\u003e\u003cbr\u003eIn research models LL-37 binds negatively charged microbial membranes, folds into an alpha helix and disrupts the bilayer, killing bacteria and fungi and inactivating enveloped viruses. It also signals to host cells through formyl peptide receptor 2, the P2X7 receptor and EGFR, recruiting immune cells and promoting epithelial migration, and it neutralises lipopolysaccharide. This combination of direct killing and immune modulation is what distinguishes it from conventional antibiotics.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does the research show about LL-37?\u003c\/strong\u003e\u003cbr\u003eIn-vitro studies show broad antimicrobial and antibiofilm activity, including against antibiotic-resistant strains, and cell and animal models report faster re-epithelialisation and angiogenesis in wounds. Research also links low cathelicidin levels to chronic ulcers and respiratory infection, and shows that vitamin D induces its expression. At the same time, LL-37 complexes with self-nucleic acids can drive inflammation in psoriasis models, so research focuses on context and concentration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I buy LL-37 at Chemist Warehouse or a pharmacy in Australia?\u003c\/strong\u003e\u003cbr\u003eNo. LL-37 is not a registered medicine in Australia and is not stocked by Chemist Warehouse, Priceline or other retail pharmacies. There is no approved LL-37 medicine anywhere in the world; the peptide remains at the preclinical and early clinical stage. The lyophilised research-grade compound sold here is supplied strictly for laboratory use and is not a pharmacy product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan Australian compounding pharmacies supply LL-37?\u003c\/strong\u003e\u003cbr\u003eLL-37 is not a compound that Australian compounding pharmacies routinely prepare, and any compounded peptide product would require an individual prescription under a pathway the TGA has placed under close scrutiny in its 2026 guidance on unapproved peptide products. Omega Peptides Australia is a research supplier: we supply the lyophilised compound for laboratory use and do not compound, prescribe or dispense medicines.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do you reconstitute LL-37?\u003c\/strong\u003e\u003cbr\u003eSwab the stopper and add bacteriostatic water slowly down the inside wall of the vial so the stream does not hit the powder directly. Swirl gently until the solution is clear; do not shake, because a long cationic peptide can aggregate or foam when agitated. Label the vial with the date and concentration, refrigerate at 2–8°C and use within 28 days. Our reconstitution calculator gives the concentration for any diluent volume.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow should LL-37 be stored?\u003c\/strong\u003e\u003cbr\u003eKeep the lyophilised vial at 2–8°C for short-term use or at −20°C for long-term storage, protected from light and moisture. The freeze-dried powder is stable for many months under these conditions. Once reconstituted, store the solution at 2–8°C and use it within 28 days, and avoid repeated freeze-thaw cycles, which promote aggregation and hydrolysis of the long peptide chain.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhere can I buy LL-37 in Australia?\u003c\/strong\u003e\u003cbr\u003eOmega Peptides Australia holds LL-37 in domestic stock, so orders placed before 12pm are dispatched the same day without international shipping delays or customs uncertainty. Every batch carries an independent Certificate of Analysis, and the compound sits within our \u003ca href=\"\/collections\/research-peptides-australia\"\u003eresearch peptides collection\u003c\/a\u003e alongside Thymosin Alpha-1, KPV and other immune research peptides.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does LL-37 cost in Australia?\u003c\/strong\u003e\u003cbr\u003eA 5mg vial of LL-37 costs $119.99 from Omega Peptides Australia, which is about $24.00 per mg. The higher per-milligram cost reflects the length and purification demands of a 37-residue peptide. There is no bundle for this compound at present, and bacteriostatic water is available separately in 3mL and 10mL sizes. Pricing is per vial and per milligram only.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do I get LL-37 online in Australia?\u003c\/strong\u003e\u003cbr\u003eSelect the 5mg vial on this product page, add any bacteriostatic water or syringes you need, and complete checkout. Orders placed before 12pm are dispatched the same day from within Australia with tracked domestic shipping in plain, discreet packaging. A tracking number is emailed when the parcel is lodged, and most metropolitan addresses receive their order within a few business days.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs LL-37 legal in Australia?\u003c\/strong\u003e\u003cbr\u003eOmega Peptides Australia supplies LL-37 strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine or supplement. Purchasers are responsible for ensuring their intended use complies with all applicable laws, including any state or territory requirements that apply to their laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do LL-37, KPV and Thymosin Alpha-1 compare as immune research peptides?\u003c\/strong\u003e\u003cbr\u003eThey act on different arms of immunity. LL-37 is an innate antimicrobial peptide that kills microbes directly and signals to immune cells. \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e is a three-residue alpha-MSH fragment studied for anti-inflammatory signalling through melanocortin pathways and NF-kB inhibition, with no direct antimicrobial effect. \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e is a thymic peptide that acts on adaptive immunity through dendritic cell and T-cell maturation. Researchers choose between them by the pathway under study.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e⚠ For in-vitro research and laboratory use only. Not for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is LL-37?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"LL-37 is the human cathelicidin antimicrobial peptide, a 37-amino-acid cationic peptide cleaved from the precursor protein hCAP-18 and produced by neutrophils, macrophages and epithelial cells as part of innate immunity. It has a molecular weight of about 4,493 daltons and forms an amphipathic alpha helix on membranes. Omega Peptides Australia supplies it as a lyophilised research-grade powder in 5mg vials for in-vitro laboratory use.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is LL-37 also known as?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"It is also written as LL37, ll 37 or LL-37 peptide, and is often called cathelicidin LL-37 or human cathelicidin. Because it is cut from the precursor hCAP-18, it is sometimes labelled the CAP-18 fragment, and an early 39-residue form was named FALL-39. All of these names refer to the same human antimicrobial peptide.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How does LL-37 work?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"In research models LL-37 binds negatively charged microbial membranes, folds into an alpha helix and disrupts the bilayer, killing bacteria and fungi and inactivating enveloped viruses. It also signals to host cells through formyl peptide receptor 2, the P2X7 receptor and EGFR, recruiting immune cells and promoting epithelial migration, and it neutralises lipopolysaccharide. This combination of direct killing and immune modulation is what distinguishes it from conventional antibiotics.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What does the research show about LL-37?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"In-vitro studies show broad antimicrobial and antibiofilm activity, including against antibiotic-resistant strains, and cell and animal models report faster re-epithelialisation and angiogenesis in wounds. Research also links low cathelicidin levels to chronic ulcers and respiratory infection, and shows that vitamin D induces its expression. At the same time, LL-37 complexes with self-nucleic acids can drive inflammation in psoriasis models, so research focuses on context and concentration.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can I buy LL-37 at Chemist Warehouse or a pharmacy in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"No. LL-37 is not a registered medicine in Australia and is not stocked by Chemist Warehouse, Priceline or other retail pharmacies. There is no approved LL-37 medicine anywhere in the world; the peptide remains at the preclinical and early clinical stage. The lyophilised research-grade compound sold here is supplied strictly for laboratory use and is not a pharmacy product.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can Australian compounding pharmacies supply LL-37?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"LL-37 is not a compound that Australian compounding pharmacies routinely prepare, and any compounded peptide product would require an individual prescription under a pathway the TGA has placed under close scrutiny in its 2026 guidance on unapproved peptide products. Omega Peptides Australia is a research supplier: we supply the lyophilised compound for laboratory use and do not compound, prescribe or dispense medicines.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do you reconstitute LL-37?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Swab the stopper and add bacteriostatic water slowly down the inside wall of the vial so the stream does not hit the powder directly. Swirl gently until the solution is clear; do not shake, because a long cationic peptide can aggregate or foam when agitated. Label the vial with the date and concentration, refrigerate at 2-8 degrees Celsius and use within 28 days. Our reconstitution calculator gives the concentration for any diluent volume.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should LL-37 be stored?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Keep the lyophilised vial at 2-8 degrees Celsius for short-term use or at −20 degrees Celsius for long-term storage, protected from light and moisture. The freeze-dried powder is stable for many months under these conditions. Once reconstituted, store the solution at 2-8 degrees Celsius and use it within 28 days, and avoid repeated freeze-thaw cycles, which promote aggregation and hydrolysis of the long peptide chain.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy LL-37 in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Omega Peptides Australia holds LL-37 in domestic stock, so orders placed before 12pm are dispatched the same day without international shipping delays or customs uncertainty. Every batch carries an independent Certificate of Analysis, and the compound sits within our research peptides collection alongside Thymosin Alpha-1, KPV and other immune research peptides.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What does LL-37 cost in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"A 5mg vial of LL-37 costs $119.99 from Omega Peptides Australia, which is about $24.00 per mg. The higher per-milligram cost reflects the length and purification demands of a 37-residue peptide. There is no bundle for this compound at present, and bacteriostatic water is available separately in 3mL and 10mL sizes. Pricing is per vial and per milligram only.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do I get LL-37 online in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Select the 5mg vial on this product page, add any bacteriostatic water or syringes you need, and complete checkout. Orders placed before 12pm are dispatched the same day from within Australia with tracked domestic shipping in plain, discreet packaging. A tracking number is emailed when the parcel is lodged, and most metropolitan addresses receive their order within a few business days.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is LL-37 legal in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Omega Peptides Australia supplies LL-37 strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine or supplement. Purchasers are responsible for ensuring their intended use complies with all applicable laws, including any state or territory requirements that apply to their laboratory.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do LL-37, KPV and Thymosin Alpha-1 compare as immune research peptides?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"They act on different arms of immunity. LL-37 is an innate antimicrobial peptide that kills microbes directly and signals to immune cells. KPV is a three-residue alpha-MSH fragment studied for anti-inflammatory signalling through melanocortin pathways and NF-kB inhibition, with no direct antimicrobial effect. Thymosin Alpha-1 is a thymic peptide that acts on adaptive immunity through dendritic cell and T-cell maturation. Researchers choose between them by the pathway under study.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e\n","brand":"Omega Peptides Australia","offers":[{"title":"5mg","offer_id":43208924266558,"sku":"LL-37-5MG","price":99.99,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0673\/2123\/3470\/files\/ll-37.png?v=1787063506"},{"product_id":"ara-290","title":"ARA-290","description":"\u003ch2\u003eARA-290 (10mg) — Innate Repair Receptor Agonist Research Peptide\u003c\/h2\u003e\n\u003cp\u003eARA-290 (10mg) is supplied in Australia by Omega Peptides Australia from domestic stock, with same-day dispatch on orders placed before 12pm and an independent certificate of analysis for every batch. Commonly written as ARA 290, cibinetide, ARA290 or innate repair receptor agonist, it is an erythropoietin-derived undecapeptide studied for innate repair receptor signalling.\u003c\/p\u003e\n\u003cp\u003eARA-290 is a synthetic 11-amino-acid peptide engineered from the three-dimensional structure of erythropoietin (EPO). It reproduces the surface of EPO's helix B, the region that contacts the tissue-protective receptor, while leaving out the parts of the hormone that stimulate red blood cell production, which is why it is described as a non-erythropoietic EPO derivative or helix B surface peptide. The sequence begins with a pyroglutamate residue and is written pGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser, giving a molecular weight of about 1,257 daltons. Its international non-proprietary name is cibinetide, and it is often written as ARA 290, ARA290 or ara290 peptide and sometimes called an innate repair receptor agonist.\u003c\/p\u003e\n\u003cp\u003eARA-290 is studied mainly in three areas: small fibre neuropathy and neuropathic pain, metabolic and microvascular complications of diabetes, and tissue protection after ischaemic or inflammatory injury in the kidney, heart and nervous system. It works by selectively activating the innate repair receptor, a heteromer formed by the erythropoietin receptor and the beta-common receptor (CD131), which is expressed on stressed cells and triggers anti-apoptotic, anti-inflammatory and repair-promoting signalling without engaging the EPO receptor homodimer that drives erythropoiesis.\u003c\/p\u003e\n\u003cp\u003eOmega Peptides Australia supplies ARA-290 as a high-purity (≥99% HPLC) COA-verified lyophilised powder in a sealed sterile 10mg vial. Orders placed before 12pm are dispatched the same day from within Australia, and the batch Certificate of Analysis for every lot is published in our \u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCOA library\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSmall fibre neuropathy\u003c\/strong\u003e The best-known clinical research on cibinetide is a series of Phase 2 studies in sarcoidosis-associated small fibre neuropathy, where investigators measured neuropathic symptoms and used corneal confocal microscopy to count small nerve fibres. Increased corneal nerve fibre density after treatment is the finding most often cited, and it supported orphan drug and fast track designations in the United States for this indication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiabetic neuropathy and metabolic markers\u003c\/strong\u003e Phase 2 work in type 2 diabetes with small fibre neuropathy examined nerve fibre regeneration in skin and cornea alongside metabolic end points such as HbA1c and lipid measures. The proposed mechanism is protection of Schwann cells and small sensory neurons from metabolic stress via innate repair receptor signalling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIschaemia-reperfusion injury\u003c\/strong\u003e Preclinical rodent models of kidney, heart and brain ischaemia have used ARA-290 and its parent helix B peptide to test whether activating the innate repair receptor reduces infarct size and apoptosis. Because the peptide does not raise haematocrit, it avoids the thrombotic concerns that limited EPO itself in these models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKidney transplantation and renal protection\u003c\/strong\u003e Clinical research has explored cibinetide as a means of limiting delayed graft function after kidney transplantation, building on animal work showing reduced tubular injury and inflammation. This remains an investigational use with mixed results across studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammation and macrophage polarisation\u003c\/strong\u003e In cell and animal models ARA-290 shifts macrophages away from a pro-inflammatory state and reduces cytokine release, which is why it is studied in inflammatory pain, wound and autoimmune models. The innate repair receptor is expressed on immune cells as well as on injured tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotection and cognition\u003c\/strong\u003e Because EPO-derived signalling supports neuronal survival, ARA-290 has been examined in models of traumatic and metabolic nerve injury and in early work on mood and cognitive end points. Development for depressive disorders was discontinued, but the neuroprotective rationale continues to drive preclinical interest.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eARA-290 in Australia\u003c\/h2\u003e\n\u003cp\u003eARA-290 is not registered on the Australian Register of Therapeutic Goods, so it is not stocked by Chemist Warehouse, Priceline or other pharmacies. In Australia it is supplied as a research-grade lyophilised vial by domestic research suppliers. Omega Peptides Australia holds ARA-290 in stock within Australia and dispatches orders placed before 12pm the same business day on tracked domestic delivery, so material arrives in days rather than waiting on an international shipment and customs. Every batch is tested independently and its certificate is published in the \u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCOA library\u003c\/a\u003e before the vial ships. Browse the full range of \u003ca href=\"\/\"\u003eresearch peptides in Australia\u003c\/a\u003e on our homepage.\u003c\/p\u003e\n\u003cp\u003eARA-290 is stocked in Australia as a 10mg vial in the tissue-repair range alongside \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e and \u003ca href=\"\/products\/tb-500\"\u003eTB-500\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eHow ARA-290 works\u003c\/h2\u003e\n\u003cp\u003eErythropoietin signals through two different receptor assemblies. The classical EPO receptor homodimer, found on erythroid progenitors, drives red blood cell production and is activated at picomolar concentrations of circulating EPO. A second assembly, the innate repair receptor, pairs one EPO receptor subunit with the beta-common receptor CD131 shared by the GM-CSF, IL-3 and IL-5 receptors. This heteromer has lower affinity for EPO, appears mainly on cells exposed to injury or metabolic stress, and triggers pathways such as JAK2-STAT, PI3K-Akt and NF-kB inhibition that reduce apoptosis, dampen inflammation and promote repair. ARA-290 was designed to mimic only the helix B face of EPO that contacts this heteromer, so it activates innate repair signalling without binding the homodimer or stimulating erythropoiesis.\u003c\/p\u003e\n\u003cp\u003eARA-290 has a very short plasma half-life, reported in the order of minutes in preclinical pharmacokinetic work, yet its biological effects persist far longer because receptor activation sets off downstream gene expression changes that continue after the peptide has cleared. This decoupling of exposure from effect is a distinctive feature of the compound. It differs from BPC-157 and TB-500, whose tissue-repair research centres on angiogenesis, growth factor expression and actin dynamics rather than on a defined receptor, and from GLP-1 class peptides, with which it shares nothing beyond peptide chemistry.\u003c\/p\u003e\n\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCompound\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eARA-290 (cibinetide)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAlso known as\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCibinetide, ARA 290, ARA290, ara290 peptide, pyroglutamate helix B surface peptide (pHBSP), innate repair receptor agonist\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1208243-50-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC51H84N16O21\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1257.3 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003epGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser (11 residues, N-terminal pyroglutamate)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCategory\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eTissue-repair research\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≥99% HPLC, batch COA supplied\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder in a sealed sterile vial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVial sizes available\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10mg — $129.99\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (lyophilised)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2–8°C short term or −20°C long term, protect from light and moisture, avoid repeated freeze-thaw\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (reconstituted)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2–8°C, use within 28 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water (recommended)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\n\u003ch2\u003eAvailable sizes and pricing\u003c\/h2\u003e\n\u003cp\u003eARA-290 is offered in a single 10mg vial. Pricing is per vial, with the equivalent per-milligram figure shown so it can be compared with other tissue-repair research peptides in the range.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e10mg vial — $129.99 (about $13.00 per mg)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMulti-vial pricing (10mg):\u003c\/strong\u003e 2 vials $233.98 (10% off, $116.99 each), 3 vials $341.22 (12.5% off, $113.74 each), 4 vials $441.97 (15% off, $110.49 each). The discount is applied automatically in the cart.\u003c\/p\u003e\n\u003cp\u003eThere is no dedicated kit for ARA-290. A 10mL vial of \u003ca href=\"\/products\/bacteriostatic-water\"\u003ebacteriostatic water\u003c\/a\u003e is the usual companion purchase and will reconstitute several vials.\u003c\/p\u003e\n\n\u003ch2\u003eQuality and COA verification\u003c\/h2\u003e\n\u003cp\u003eEvery batch of ARA-290 sold by Omega Peptides Australia is independently tested by Janoshik Analytical. HPLC confirms purity of ≥99%, and mass spectrometry confirms that the measured mass matches the expected 1,257 daltons of cibinetide, including the N-terminal pyroglutamate that distinguishes it from the open-chain glutamine form. A Certificate of Analysis is issued for every batch and published in our \u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCOA library\u003c\/a\u003e, where the batch number on your vial can be matched to its report. The peptide is supplied lyophilised in a sealed sterile vial because the freeze-dried form is stable for months in the cold, whereas solutions degrade over weeks. Vials are packed in protective outer packaging for domestic transit.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently bought together\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/bacteriostatic-water\"\u003eBacteriostatic Water (10mL)\u003c\/a\u003e — $29.99, the diluent used to reconstitute lyophilised ARA-290.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/bpc-157\"\u003eBPC-157 (10mg)\u003c\/a\u003e — $99.99, the pentadecapeptide most often compared with ARA-290 in tissue-repair research.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/tb-500\"\u003eTB-500 (10mg)\u003c\/a\u003e — $99.99, the thymosin beta-4 fragment studied in cell migration and repair models.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/ll-37\"\u003eLL-37 (5mg)\u003c\/a\u003e — $119.99, the antimicrobial peptide studied in wound and innate immunity models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch guides\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/peptide-storage-guide-how-to-store-lyophilised-peptides-properly\"\u003ePeptide storage guide: how to store lyophilised peptides properly\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/coa-testing-explained-research-peptides-australia\"\u003eCOA testing explained for research peptides in Australia\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/bpc-157-vs-tb-500\"\u003eBPC-157 vs TB-500 comparison\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/research-calculator\"\u003ePeptide reconstitution calculator\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCertificates of Analysis library\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is ARA-290?\u003c\/strong\u003e\u003cbr\u003eARA-290 is a synthetic 11-amino-acid peptide derived from the helix B region of erythropoietin, designed to activate the tissue-protective innate repair receptor without stimulating red blood cell production. Its international non-proprietary name is cibinetide and its molecular weight is about 1,257 daltons. Omega Peptides Australia supplies it as a lyophilised research-grade powder in 10mg vials for in-vitro laboratory use, with an independent Certificate of Analysis for every batch.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is ARA-290 also known as?\u003c\/strong\u003e\u003cbr\u003eIt is also written as ARA 290, ARA290 or ara290 peptide, and its generic name is cibinetide. In the scientific literature it is described as pyroglutamate helix B surface peptide (pHBSP), a non-erythropoietic EPO derivative or an innate repair receptor agonist. All of these names refer to the same 11-residue peptide with CAS number 1208243-50-8.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does ARA-290 work?\u003c\/strong\u003e\u003cbr\u003eIn research models ARA-290 binds the innate repair receptor, a complex of the erythropoietin receptor and the beta-common receptor CD131 that appears on cells under stress. Activation triggers JAK2-STAT and PI3K-Akt signalling and inhibits NF-kB, which reduces apoptosis, limits inflammatory cytokine release and promotes repair. Because it cannot engage the EPO receptor homodimer, it does not raise haematocrit, which separates it from erythropoietin itself.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does the research show about ARA-290?\u003c\/strong\u003e\u003cbr\u003ePhase 2 clinical programs in sarcoidosis-associated and diabetic small fibre neuropathy reported improved neuropathic symptoms and increased corneal and skin nerve fibre density. Preclinical rodent models report protection in kidney, heart and brain ischaemia and reduced inflammation in wound and pain models. Development did not proceed to Phase 3, so cibinetide remains an investigational compound and the clinical evidence is limited to small studies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I buy ARA-290 at Chemist Warehouse or a pharmacy in Australia?\u003c\/strong\u003e\u003cbr\u003eNo. ARA-290 is not a registered medicine in Australia or anywhere else, and it is not stocked by Chemist Warehouse, Priceline or other retail pharmacies. Cibinetide never advanced beyond Phase 2 trials and has no approved pharmaceutical form. The lyophilised research-grade compound sold here is supplied strictly for laboratory use and is not a pharmacy product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan Australian compounding pharmacies supply ARA-290?\u003c\/strong\u003e\u003cbr\u003eARA-290 is not a compound that Australian compounding pharmacies routinely prepare, and any compounded peptide product would require an individual prescription under a pathway the TGA has placed under close scrutiny in its 2026 guidance on unapproved peptide products. Omega Peptides Australia is a research supplier: we supply the lyophilised compound for laboratory use and do not compound, prescribe or dispense medicines.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do you reconstitute ARA-290?\u003c\/strong\u003e\u003cbr\u003eSwab the stopper and add bacteriostatic water slowly down the inside wall of the vial so the stream does not hit the powder directly. Swirl gently until the solution is clear; do not shake. Label the vial with the date and concentration, refrigerate at 2–8°C and use within 28 days. ARA-290 dissolves readily in water, and our reconstitution calculator gives the concentration for any diluent volume.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow should ARA-290 be stored?\u003c\/strong\u003e\u003cbr\u003eKeep the lyophilised vial at 2–8°C for short-term use or at −20°C for long-term storage, protected from light and moisture. The freeze-dried powder is stable for many months under these conditions. Once reconstituted, store the solution at 2–8°C and use it within 28 days, and avoid repeated freeze-thaw cycles, which accelerate hydrolysis of the peptide bonds and deamidation of the asparagine and glutamine residues.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhere can I buy ARA-290 in Australia?\u003c\/strong\u003e\u003cbr\u003eOmega Peptides Australia holds ARA-290 in domestic stock, so orders placed before 12pm are dispatched the same day without international shipping delays or customs uncertainty. Every batch carries an independent Certificate of Analysis, and the compound sits within our \u003ca href=\"\/collections\/research-peptides-australia\"\u003eresearch peptides collection\u003c\/a\u003e alongside BPC-157, TB-500 and other tissue-repair research peptides.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does ARA-290 cost in Australia?\u003c\/strong\u003e\u003cbr\u003eA 10mg vial of ARA-290 costs $129.99 from Omega Peptides Australia, which is about $13.00 per mg. There is no bundle for this compound at present, and bacteriostatic water is available separately in 3mL and 10mL sizes for reconstitution. Pricing is expressed per vial and per milligram only, as the product is supplied for laboratory use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do I get ARA-290 online in Australia?\u003c\/strong\u003e\u003cbr\u003eSelect the 10mg vial on this product page, add any bacteriostatic water or syringes you need, and complete checkout. Orders placed before 12pm are dispatched the same day from within Australia with tracked domestic shipping in plain, discreet packaging. A tracking number is emailed when the parcel is lodged, and most metropolitan addresses receive their order within a few business days.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs ARA-290 legal in Australia?\u003c\/strong\u003e\u003cbr\u003eOmega Peptides Australia supplies ARA-290 strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine or supplement. Purchasers are responsible for ensuring their intended use complies with all applicable laws, including any state or territory requirements that apply to their laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do ARA-290 and BPC-157 differ in tissue-repair research?\u003c\/strong\u003e\u003cbr\u003eARA-290 acts through a defined receptor, the innate repair receptor, and its research centres on nerve fibre regeneration, neuropathic pain and protection from ischaemic injury. \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e is a 15-residue gastric peptide with no single identified receptor whose research centres on tendon, ligament, muscle and gut repair through angiogenesis and growth factor expression. They are studied for different questions, and ARA-290 is the more expensive compound per milligram because of its clinical development history.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs ARA-290 available in Australia?\u003c\/strong\u003e\u003cbr\u003eYes, as a research-grade lyophilised peptide from domestic suppliers. Omega Peptides Australia holds ARA-290 10mg in Australian stock, COA verified, with same-day dispatch before 12pm.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhere can I buy ARA 290 in Australia?\u003c\/strong\u003e\u003cbr\u003eFrom an Australian research peptide supplier holding domestic stock. Omega Peptides Australia dispatches ARA-290 from within Australia on tracked delivery.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e⚠ For in-vitro research and laboratory use only. Not for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is ARA-290?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"ARA-290 is a synthetic 11-amino-acid peptide derived from the helix B region of erythropoietin, designed to activate the tissue-protective innate repair receptor without stimulating red blood cell production. Its international non-proprietary name is cibinetide and its molecular weight is about 1,257 daltons. Omega Peptides Australia supplies it as a lyophilised research-grade powder in 10mg vials for in-vitro laboratory use, with an independent Certificate of Analysis for every batch.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is ARA-290 also known as?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"It is also written as ARA 290, ARA290 or ara290 peptide, and its generic name is cibinetide. In the scientific literature it is described as pyroglutamate helix B surface peptide (pHBSP), a non-erythropoietic EPO derivative or an innate repair receptor agonist. All of these names refer to the same 11-residue peptide with CAS number 1208243-50-8.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How does ARA-290 work?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"In research models ARA-290 binds the innate repair receptor, a complex of the erythropoietin receptor and the beta-common receptor CD131 that appears on cells under stress. Activation triggers JAK2-STAT and PI3K-Akt signalling and inhibits NF-kB, which reduces apoptosis, limits inflammatory cytokine release and promotes repair. Because it cannot engage the EPO receptor homodimer, it does not raise haematocrit, which separates it from erythropoietin itself.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What does the research show about ARA-290?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Phase 2 clinical programs in sarcoidosis-associated and diabetic small fibre neuropathy reported improved neuropathic symptoms and increased corneal and skin nerve fibre density. Preclinical rodent models report protection in kidney, heart and brain ischaemia and reduced inflammation in wound and pain models. Development did not proceed to Phase 3, so cibinetide remains an investigational compound and the clinical evidence is limited to small studies.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can I buy ARA-290 at Chemist Warehouse or a pharmacy in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"No. ARA-290 is not a registered medicine in Australia or anywhere else, and it is not stocked by Chemist Warehouse, Priceline or other retail pharmacies. Cibinetide never advanced beyond Phase 2 trials and has no approved pharmaceutical form. The lyophilised research-grade compound sold here is supplied strictly for laboratory use and is not a pharmacy product.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can Australian compounding pharmacies supply ARA-290?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"ARA-290 is not a compound that Australian compounding pharmacies routinely prepare, and any compounded peptide product would require an individual prescription under a pathway the TGA has placed under close scrutiny in its 2026 guidance on unapproved peptide products. Omega Peptides Australia is a research supplier: we supply the lyophilised compound for laboratory use and do not compound, prescribe or dispense medicines.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do you reconstitute ARA-290?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Swab the stopper and add bacteriostatic water slowly down the inside wall of the vial so the stream does not hit the powder directly. Swirl gently until the solution is clear; do not shake. Label the vial with the date and concentration, refrigerate at 2-8 degrees Celsius and use within 28 days. ARA-290 dissolves readily in water, and our reconstitution calculator gives the concentration for any diluent volume.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should ARA-290 be stored?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Keep the lyophilised vial at 2-8 degrees Celsius for short-term use or at −20 degrees Celsius for long-term storage, protected from light and moisture. The freeze-dried powder is stable for many months under these conditions. Once reconstituted, store the solution at 2-8 degrees Celsius and use it within 28 days, and avoid repeated freeze-thaw cycles, which accelerate hydrolysis of the peptide bonds and deamidation of the asparagine and glutamine residues.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy ARA-290 in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Omega Peptides Australia holds ARA-290 in domestic stock, so orders placed before 12pm are dispatched the same day without international shipping delays or customs uncertainty. Every batch carries an independent Certificate of Analysis, and the compound sits within our research peptides collection alongside BPC-157, TB-500 and other tissue-repair research peptides.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What does ARA-290 cost in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"A 10mg vial of ARA-290 costs $129.99 from Omega Peptides Australia, which is about $13.00 per mg. There is no bundle for this compound at present, and bacteriostatic water is available separately in 3mL and 10mL sizes for reconstitution. Pricing is expressed per vial and per milligram only, as the product is supplied for laboratory use.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do I get ARA-290 online in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Select the 10mg vial on this product page, add any bacteriostatic water or syringes you need, and complete checkout. Orders placed before 12pm are dispatched the same day from within Australia with tracked domestic shipping in plain, discreet packaging. A tracking number is emailed when the parcel is lodged, and most metropolitan addresses receive their order within a few business days.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is ARA-290 legal in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Omega Peptides Australia supplies ARA-290 strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine or supplement. Purchasers are responsible for ensuring their intended use complies with all applicable laws, including any state or territory requirements that apply to their laboratory.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do ARA-290 and BPC-157 differ in tissue-repair research?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"ARA-290 acts through a defined receptor, the innate repair receptor, and its research centres on nerve fibre regeneration, neuropathic pain and protection from ischaemic injury. BPC-157 is a 15-residue gastric peptide with no single identified receptor whose research centres on tendon, ligament, muscle and gut repair through angiogenesis and growth factor expression. They are studied for different questions, and ARA-290 is the more expensive compound per milligram because of its clinical development history.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is ARA-290 available in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes, as a research-grade lyophilised peptide from domestic suppliers. Omega Peptides Australia holds ARA-290 10mg in Australian stock, COA verified, with same-day dispatch before 12pm.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy ARA 290 in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"From an Australian research peptide supplier holding domestic stock. Omega Peptides Australia dispatches ARA-290 from within Australia on tracked delivery.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e\n","brand":"Omega Peptides Australia","offers":[{"title":"10mg","offer_id":43208927313982,"sku":"ARA-290-10MG","price":129.99,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0673\/2123\/3470\/files\/ara290_10mg.png?v=1787063517"},{"product_id":"adamax","title":"Adamax","description":"\u003ch2\u003eAdamax (10mg) — Adamantane-Modified Semax Analogue Research Peptide\u003c\/h2\u003e\n\u003cp\u003eOmega Peptides Australia supplies Adamax (10mg) in Australia from domestic stock, dispatching same day on orders placed before 12pm with a certificate of analysis published for every batch. Often written adamax peptide or adamantane semax, it is an adamantane-modified Semax analogue studied for neuroprotection.\u003c\/p\u003e\n\u003cp\u003eAdamax is a synthetic research peptide described as an adamantane-modified analogue of Semax, the heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro. Semax itself was built from the ACTH(4-7) fragment of adrenocorticotropic hormone with a Pro-Gly-Pro extension added at the C-terminus to slow enzymatic breakdown, and it has been studied in Russian laboratories for several decades. Adamax takes that backbone and, according to supplier descriptions, attaches an adamantyl group, the rigid cage-shaped hydrocarbon found in compounds such as amantadine and memantine. It is often written as Adamax peptide, ADMAX or adamax nootropic peptide, and is sometimes described as an adamantane Semax analogue or adamantylated Semax.\u003c\/p\u003e\n\u003cp\u003eAdamax is investigated in the same research directions as its parent peptide: neurotrophic signalling, particularly brain-derived neurotrophic factor (BDNF) expression, learning and memory performance in rodent models, and neuroprotection under ischaemic or oxidative stress. The Semax family is thought to act by raising BDNF and its receptor TrkB in the hippocampus and by modulating monoamine and enkephalin systems, while the adamantane group is intended to increase lipophilicity and resistance to peptidases so that the molecule persists longer in tissue.\u003c\/p\u003e\n\u003cp\u003eOmega Peptides Australia supplies Adamax as a high-purity (≥99% HPLC) COA-verified lyophilised powder in a sealed sterile 10mg vial. Orders placed before 12pm are dispatched the same day from within Australia, and the batch certificate for every lot is published in our \u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCOA library\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurotrophic signalling\u003c\/strong\u003e Semax has been shown in rodent studies to increase BDNF and TrkB expression in the hippocampus within hours of administration. Adamax is studied to establish whether the adamantane substitution preserves or amplifies that neurotrophic response in cultured neurons and rodent brain tissue, and whether the effect persists longer because of slower peptidase clearance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLearning and memory\u003c\/strong\u003e The Semax lineage has been examined in rodent behavioural tasks such as passive avoidance and maze learning, where melanocortin fragments are associated with improved acquisition and retention. Adamax is investigated as a comparator in the same paradigms, with the working hypothesis that a more lipophilic analogue may reach central targets more efficiently.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotection\u003c\/strong\u003e Semax has been studied in models of cerebral ischaemia and retinal or optic nerve injury, where it is associated with reduced neuronal loss and altered expression of genes involved in inflammation and apoptosis. Adamax is examined for the same protective profile, with attention to whether the adamantyl group changes tissue distribution during hypoxic stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStress and anxiety-related behaviour\u003c\/strong\u003e ACTH-derived fragments modulate the hypothalamic-pituitary-adrenal axis and anxiety-like behaviour in rodents without producing classical corticosteroid release. Adamax is studied in elevated plus maze and open field paradigms to determine whether the modified peptide shares this anxiolytic-type profile.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEndurance and recovery\u003c\/strong\u003e Supplier literature describes Adamax as being of interest for physical endurance and recovery from strenuous exertion. This claim does not yet appear in peer-reviewed research and should be treated as a hypothesis for rodent exercise models rather than an established finding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStructure-activity relationships\u003c\/strong\u003e Because Semax, N-Acetyl Semax and Adamax share a backbone and differ only in their terminal or lipophilic modifications, the three are used together in comparative studies of peptide stability, blood-brain barrier passage and potency, helping researchers understand how small chemical changes alter the behaviour of melanocortin-derived peptides.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow Adamax works\u003c\/h2\u003e\n\u003cp\u003eAdamax is expected to act through the same pathways as Semax. Semax is a melanocortin-derived heptapeptide that does not behave as a classical agonist at melanocortin receptors; instead, it has been reported to raise BDNF and nerve growth factor expression, increase TrkB receptor levels in the hippocampus, modulate serotonergic and dopaminergic transmission, and inhibit enzymes that degrade enkephalins. Together these actions are proposed to underpin the memory, attention and neuroprotective findings reported in rodent and in-vitro research. Adamax retains the Semax backbone, so its research rationale rests on those established mechanisms.\u003c\/p\u003e\n\u003cp\u003eWhat distinguishes Adamax is the adamantane cage. Adamantane is highly lipophilic and sterically bulky, which in medicinal chemistry is used to improve membrane penetration and to shield adjacent bonds from enzymatic cleavage. Native Semax is degraded quickly by peptidases, with a half-life measured in minutes, and N-Acetyl Semax addresses this with an acetyl group on the N-terminus. Adamax pursues the same goal with a larger lipophilic modification. No peer-reviewed pharmacokinetic data for Adamax have been published, so its actual half-life and distribution in research models remain to be characterised, and each batch is confirmed by HPLC purity and mass spectrometry identity rather than by a published reference monograph.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCompound\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAdamax (adamantane-modified Semax analogue)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAlso known as\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAdamax peptide, ADMAX, adamantane Semax analogue, adamax nootropic peptide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCategory\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eNootropic research\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≥99% HPLC, batch COA supplied\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder in a sealed sterile vial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVial sizes available\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10mg — $159.99\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (lyophilised)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2–8°C short term or −20°C long term, protect from light and moisture, avoid repeated freeze-thaw\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (reconstituted)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2–8°C, use within 28 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water (recommended)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eAvailable sizes and pricing\u003c\/h2\u003e\n\u003cp\u003eAdamax is supplied in a single 10mg research vial. Because the compound is a specialist modified analogue rather than a mass-produced peptide, the per-milligram cost is higher than Semax, which we also stock for laboratories comparing the two.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e10mg vial — $159.99 (about $16.00 per mg)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMulti-vial pricing (10mg):\u003c\/strong\u003e 2 vials $287.98 (10% off, $143.99 each), 3 vials $419.97 (12.5% off, $139.99 each), 4 vials $543.97 (15% off, $135.99 each). The discount is applied automatically in the cart.\u003c\/p\u003e\n\u003cp\u003eLaboratories building a nootropic peptide panel may also consider the \u003ca href=\"\/products\/limitless-bundle\"\u003eSemax and Selank Bundle\u003c\/a\u003e, which pairs the parent peptide with Selank at a bundle price.\u003c\/p\u003e\n\u003ch2\u003eQuality and COA verification\u003c\/h2\u003e\n\u003cp\u003eEvery batch of Adamax is tested independently by Janoshik Analytical, with HPLC used to quantify purity and mass spectrometry used to confirm molecular identity. A Certificate of Analysis is issued for every lot, and the current batch certificate can be viewed in our \u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCOA library\u003c\/a\u003e before or after purchase. Because Adamax has no published pharmacopoeial monograph, the mass spectrometry identity check is particularly important, and we will not release a batch that does not match the expected mass. The peptide is lyophilised to protect it from hydrolysis during storage, sealed in a sterile vial under an inert environment, and packed with cushioning for domestic transit so that it arrives ready for laboratory use.\u003c\/p\u003e\n\u003ch2\u003eFrequently bought together\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/semax\"\u003eSemax (10mg)\u003c\/a\u003e — $79.99, the parent heptapeptide, essential as a comparator in any Adamax study\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/n-acetyl-semax\"\u003eN-Acetyl Semax (10mg)\u003c\/a\u003e — $129.99, the acetylated analogue for structure-activity comparisons\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/dihexa\"\u003eDihexa (10mg)\u003c\/a\u003e — $169.99, a mechanistically distinct HGF\/c-Met research compound often studied alongside melanocortin peptides\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/bacteriostatic-water\"\u003eBacteriostatic Water (10mL)\u003c\/a\u003e — $29.99, for reconstituting the lyophilised powder\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eResearch guides\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/semax-australia-research-guide\"\u003eSemax Australia research guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/peptide-storage-guide-how-to-store-lyophilised-peptides-properly\"\u003ePeptide storage guide: how to store lyophilised peptides properly\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/blogs\/news\/coa-testing-explained-research-peptides-australia\"\u003eCOA testing explained\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/research-calculator\"\u003ePeptide reconstitution calculator\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/pages\/certifications-of-analysis\"\u003eCertificates of Analysis library\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Adamax?\u003c\/strong\u003e\u003cbr\u003eAdamax is a synthetic research peptide built on the Semax backbone, Met-Glu-His-Phe-Pro-Gly-Pro, with an adamantane group added to increase lipophilicity and enzymatic stability. Semax is an ACTH(4-7) fragment analogue that has been studied for neurotrophic and cognitive effects in rodent models, and Adamax is investigated as a longer-lasting variant of that peptide. It is supplied as a lyophilised powder strictly for in-vitro research and laboratory use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Adamax also known as?\u003c\/strong\u003e\u003cbr\u003eIt is also written as Adamax peptide, ADMAX or adamax nootropic peptide, and is often described as an adamantane Semax analogue, adamantylated Semax or adamantane-modified Semax. Some listings group it with the broader family of ACTH(4-10) fragment analogues. It should not be confused with Semax or N-Acetyl Semax, which are separate compounds with their own specifications.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Adamax work?\u003c\/strong\u003e\u003cbr\u003eAdamax is expected to share the mechanism of Semax, which raises BDNF and TrkB expression in the hippocampus, modulates serotonergic and dopaminergic signalling, and inhibits enkephalin-degrading enzymes in rodent research. The adamantane cage is intended to protect the peptide from peptidase cleavage and improve membrane penetration, so that these actions last longer. Direct pharmacokinetic studies of Adamax have not yet been published.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does the research show about Adamax?\u003c\/strong\u003e\u003cbr\u003ePeer-reviewed research on Adamax itself is very limited, so most of the evidence base comes from Semax, which has been studied in rodent models of memory, cerebral ischaemia and stress and in Russian clinical programmes as a nasal formulation. Supplier reports of enhanced BDNF response and endurance in Adamax have not been independently confirmed. Researchers typically treat Adamax as an experimental analogue to be characterised against Semax in their own models.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I buy Adamax at Chemist Warehouse or a pharmacy in Australia?\u003c\/strong\u003e\u003cbr\u003eNo. Adamax is not a registered medicine on the Australian Register of Therapeutic Goods and is not stocked by Chemist Warehouse, Priceline or any other retail pharmacy. The same applies to its parent peptide Semax, which is registered only in Russia and a small number of other countries. In Australia, Adamax is available only as a research-grade lyophilised compound from laboratory suppliers, for in-vitro use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan Australian compounding pharmacies supply Adamax?\u003c\/strong\u003e\u003cbr\u003eCompounding pharmacies in Australia may only prepare a medicine for an individual patient against a prescription, and the TGA has highlighted significant uncertainties with compounded unapproved peptides whose active ingredients are not described in recognised compounding references. Adamax has no such reference and no pharmacopoeial monograph, so it is not a compounding product. Research suppliers such as Omega Peptides Australia supply the lyophilised research compound for laboratory use only.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do you reconstitute Adamax?\u003c\/strong\u003e\u003cbr\u003eUse bacteriostatic water. Draw the required volume with a sterile syringe and add it slowly down the inside wall of the vial rather than directly onto the powder. Swirl gently until the solution is clear; never shake, as agitation can denature the peptide. Adamax is more lipophilic than Semax, so allow a little extra time for it to dissolve. Refrigerate the reconstituted vial at 2–8°C and use within 28 days.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow should Adamax be stored?\u003c\/strong\u003e\u003cbr\u003eKeep the lyophilised vial sealed at 2–8°C for short-term storage or at −20°C for long-term storage, protected from light and moisture. Avoid repeated freeze-thaw cycles, which degrade peptides more quickly than steady cold storage. Once reconstituted, store the solution in the refrigerator at 2–8°C and use it within 28 days. Our storage guide covers handling in more detail.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhere can I buy Adamax in Australia?\u003c\/strong\u003e\u003cbr\u003eOmega Peptides Australia supplies Adamax from domestic stock, with orders placed before 12pm dispatched the same day and a batch COA available for every vial. Ordering from an Australian supplier avoids customs delays and the temperature swings of international transit. You can browse Adamax alongside our other neuropeptides in the \u003ca href=\"\/collections\/research-peptides-australia\"\u003eresearch peptides Australia collection\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does Adamax cost in Australia?\u003c\/strong\u003e\u003cbr\u003eAdamax is priced at $159.99 for a 10mg vial, which is about $16.00 per mg. The higher per-milligram cost compared with Semax at $79.99 reflects the additional synthesis steps required for the adamantane modification and the smaller production volumes of this analogue. All prices are in Australian dollars and include a batch Certificate of Analysis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do I get Adamax online in Australia?\u003c\/strong\u003e\u003cbr\u003eSelect the 10mg vial on this product page, add it to your cart and complete checkout. Orders are shipped with tracked domestic delivery in discreet packaging with no external reference to the contents. Orders placed before 12pm on a business day are dispatched the same day; later orders leave the next business day. You will receive tracking details by email once the parcel is lodged.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs Adamax legal in Australia?\u003c\/strong\u003e\u003cbr\u003eOmega Peptides Australia supplies Adamax strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine or supplement. Purchasers are responsible for ensuring their intended use complies with all applicable laws.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdamax vs Semax and N-Acetyl Semax: what is the difference?\u003c\/strong\u003e\u003cbr\u003eAll three share the Met-Glu-His-Phe-Pro-Gly-Pro backbone. Semax is the original, best-studied peptide. N-Acetyl Semax adds an acetyl group to the N-terminus, which slows enzymatic degradation and is the form most often used in newer research. Adamax adds a bulky adamantane group intended to increase lipophilicity and stability further, but it has the smallest published evidence base of the three. Laboratories usually run Semax as the reference compound when evaluating either analogue.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e⚠ For in-vitro research and laboratory use only. Not for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Adamax?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Adamax is a synthetic research peptide built on the Semax backbone, Met-Glu-His-Phe-Pro-Gly-Pro, with an adamantane group added to increase lipophilicity and enzymatic stability. Semax is an ACTH(4-7) fragment analogue that has been studied for neurotrophic and cognitive effects in rodent models, and Adamax is investigated as a longer-lasting variant of that peptide. It is supplied as a lyophilised powder strictly for in-vitro research and laboratory use.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Adamax also known as?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"It is also written as Adamax peptide, ADMAX or adamax nootropic peptide, and is often described as an adamantane Semax analogue, adamantylated Semax or adamantane-modified Semax. Some listings group it with the broader family of ACTH(4-10) fragment analogues. It should not be confused with Semax or N-Acetyl Semax, which are separate compounds with their own specifications.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How does Adamax work?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Adamax is expected to share the mechanism of Semax, which raises BDNF and TrkB expression in the hippocampus, modulates serotonergic and dopaminergic signalling, and inhibits enkephalin-degrading enzymes in rodent research. The adamantane cage is intended to protect the peptide from peptidase cleavage and improve membrane penetration, so that these actions last longer. Direct pharmacokinetic studies of Adamax have not yet been published.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What does the research show about Adamax?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Peer-reviewed research on Adamax itself is very limited, so most of the evidence base comes from Semax, which has been studied in rodent models of memory, cerebral ischaemia and stress and in Russian clinical programmes as a nasal formulation. Supplier reports of enhanced BDNF response and endurance in Adamax have not been independently confirmed. Researchers typically treat Adamax as an experimental analogue to be characterised against Semax in their own models.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can I buy Adamax at Chemist Warehouse or a pharmacy in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"No. Adamax is not a registered medicine on the Australian Register of Therapeutic Goods and is not stocked by Chemist Warehouse, Priceline or any other retail pharmacy. The same applies to its parent peptide Semax, which is registered only in Russia and a small number of other countries. In Australia, Adamax is available only as a research-grade lyophilised compound from laboratory suppliers, for in-vitro use.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can Australian compounding pharmacies supply Adamax?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Compounding pharmacies in Australia may only prepare a medicine for an individual patient against a prescription, and the TGA has highlighted significant uncertainties with compounded unapproved peptides whose active ingredients are not described in recognised compounding references. Adamax has no such reference and no pharmacopoeial monograph, so it is not a compounding product. Research suppliers such as Omega Peptides Australia supply the lyophilised research compound for laboratory use only.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do you reconstitute Adamax?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Use bacteriostatic water. Draw the required volume with a sterile syringe and add it slowly down the inside wall of the vial rather than directly onto the powder. Swirl gently until the solution is clear; never shake, as agitation can denature the peptide. Adamax is more lipophilic than Semax, so allow a little extra time for it to dissolve. Refrigerate the reconstituted vial at 2-8 degrees Celsius and use within 28 days.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should Adamax be stored?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Keep the lyophilised vial sealed at 2-8 degrees Celsius for short-term storage or at −20 degrees Celsius for long-term storage, protected from light and moisture. Avoid repeated freeze-thaw cycles, which degrade peptides more quickly than steady cold storage. Once reconstituted, store the solution in the refrigerator at 2-8 degrees Celsius and use it within 28 days. Our storage guide covers handling in more detail.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Adamax in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Omega Peptides Australia supplies Adamax from domestic stock, with orders placed before 12pm dispatched the same day and a batch COA available for every vial. Ordering from an Australian supplier avoids customs delays and the temperature swings of international transit. You can browse Adamax alongside our other neuropeptides in the research peptides Australia collection.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What does Adamax cost in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Adamax is priced at $159.99 for a 10mg vial, which is about $16.00 per mg. The higher per-milligram cost compared with Semax at $79.99 reflects the additional synthesis steps required for the adamantane modification and the smaller production volumes of this analogue. All prices are in Australian dollars and include a batch Certificate of Analysis.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do I get Adamax online in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Select the 10mg vial on this product page, add it to your cart and complete checkout. Orders are shipped with tracked domestic delivery in discreet packaging with no external reference to the contents. Orders placed before 12pm on a business day are dispatched the same day; later orders leave the next business day. You will receive tracking details by email once the parcel is lodged.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is Adamax legal in Australia?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Omega Peptides Australia supplies Adamax strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine or supplement. Purchasers are responsible for ensuring their intended use complies with all applicable laws.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Adamax vs Semax and N-Acetyl Semax: what is the difference?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"All three share the Met-Glu-His-Phe-Pro-Gly-Pro backbone. Semax is the original, best-studied peptide. N-Acetyl Semax adds an acetyl group to the N-terminus, which slows enzymatic degradation and is the form most often used in newer research. Adamax adds a bulky adamantane group intended to increase lipophilicity and stability further, but it has the smallest published evidence base of the three. Laboratories usually run Semax as the reference compound when evaluating either analogue.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e\n","brand":"Omega Peptides Australia","offers":[{"title":"10mg","offer_id":43208944681022,"sku":"ADAMAX-10MG","price":129.99,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0673\/2123\/3470\/files\/adamax10mg.png?v=1787063596"}],"url":"https:\/\/www.omegapeptidesaustralia.com\/collections\/frontpage.oembed","provider":"Omega Peptides Australia","version":"1.0","type":"link"}